I'm running Windows 7 with Visual Studio 2010. When I would debug web applications (where VS would use Cassini, the development web server), browser performance was extremely slow. We're talking almost a second for retrieval of every image (all on my local machine). Most of the time it seemed like IE didn't experience the problem, but something changed and it too seemed to stop working.
After coming across this post and doing what it recommended, the problem went away. I've no idea why that configuration change in Firefox would affect IE, but all my problems vanished.
Maybe this will help some other poor chap; it got to the point where I just couldn't work at all.